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Case Studies Case Study 1 (Degassing) Degassing a small volume of solvent

Company M asks for: a degassing system for a very small amount of solvent

Besides the standard products listed on this website, at FLOM we also do a lot of custom design and manufacture for the specialty needs of our customers. If you don’t see what you’re looking for here, contact us and let us know exactly what you want.

The Challenge

Company M was looking for an LC component that could handle an extremely low volume of solvent.
The vacuum chamber of the degassing unit needed to be exceptionally small but they couldn’t find anything on the market that would match their specs.

The Customer’s Plea

They came to FLOM and asked, “What’s the minimum vacuum chamber you could put on a degassing unit?”

FLOM’s Response

We proposed using a new type of degassing membrane (Teflon AF? from Dupont) with a degassing performance roughly 20 times better than conventional membranes, to ensure proper degassing in a vacuum chamber reduced down to 50μl.

Customer comment on the finished product

Customer comment on the finished productAs promised, we delivered a high performance degassing unit with an extremely small vacuum chamber.
Company M expressed their satisfaction in this comment: “What a great help you’ve been! We couldn’t find this anywhere. Thanks for the rapid response to our dilemma.”

Total Delivery Time

Initial discussion to concept/proposal: 4 weeks
Concept/proposal to working prototypes: 6 weeks
Prototypes to final delivery: 4 weeks
Total: 14 weeks
Customers have asked FLOM to make them new designs for a variety of reasons: compactness, low-cost, etc. More examples of our work can be found below.
  • Case Study 2. Successful high precision injection of super low volume samples Injector
  • Case Study 3. We need an inert-path compact pump with high pressure but low pressure variability! Pump
  • Case Study 4. Speciality valve designed for a small-lot, low-cost application Pump
  • Case Study 5. Solving problems with another company’s degassing unit Degassing
  • Case Study 6. Problems with our current pumps! Can you help us fast? Pump
  • Case Study 7. Reduced cost but performance matched! Pump
  • Case Study 8. Stabilizing degassing operation over a tiny vacuum range Degassing
See for yourself why FLOM is a frontrunner in LC components.
Why Choose FLOM?

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